Mechanism of Resistance

Enzymatic destruction, enzymatic modification, altered target and decreased uptake are the various ways by which the pathogenic organism shows resistance to the antimicrobial substance. The resistance is brought about by the alteration in the target site or the modification or the inactivation of the antibiotic, modification of metabolic pathway to reduce the antibiotic effect to the organism, decreasing the influx by decreasing the permeability. 

  • Genetic Jugglery for resistance
  • Intrinsic Resistance for survival
  • Resistome for the resistance
  • Modes and mechanisms of transmission

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