Tuberculosis and Hepatitis Co-Infections

Most of the healthy people’s immune systems kill or contain TB infection without developing symptoms. Latent TB infection is the asymptomatic and non-transmissible form of TB. Hepatitis is the inflammation of liver. There are 5 main types of hepatitis viruses, referred to as types A, B, C, D and E. Twin studies of tuberculosis (TB)  and the chronic HBV infection identified as the strong host genetic component to individual variability in case of disease susceptibility.
Short-course chemotherapy containing the combination of Rifampicin plus Isoniazid has proved to be the highly effective in treatment of tuberculosis, but one of its adverse effects is hepatotoxicity. An estimated 49 million lives are saved through TB diagnosis and treatment between 2000 and 2015. Injection drug abusers, dialysis patients, sex workers, healthcare workers, patients with HIV infection, homeless people, persons in mental hospitals or prisons, and foreign-born persons of countries with highly prevalent HBV / hepatitis C and / or TB are at risk of exposure to both HBV and TB. HBV serology status can be predicted exactly on the basis of a Questionnaire algorithm, including a history of blood transfusion, IV drug abuse, younger age at sexual debut, and multiple sexual partners
Immunodeficiency | Anti-tuberculosis therapy (ATT) | Drug-induced-hepatotoxicity (DIH) | Alcoholism | Malnutrition | Seroreversion illnesses | Patients protocols | Interferon therapy

  • Tuberculosis and STD
  • TB and HIV co-infection
  • Prevalence
  • Tuberculosis - Health impact
  • Hepatotoxicity
  • Pulmonary/Extrapulmonary TB
  • Pulmonary/Extrapulmonary TB
  • Tuberculosis in children
  • Acute hepatitis
  • Hepatitis C Coalition
  • Hepatic cirrhosis
  • Auto immune hepatitis
  • Liver disorders

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